I have been asked before on how to verify jumbo frames end-to-end for a SAN network. I think this the simplest way from an ESXi 5 host.
1. Enable SSH on your ESXi host
2. Use putty or something simliar to SSH into the ESXi host.
3. type vmkping -d -s 8972 <remote-ip-address.
Thats it. If you get a reply you should be good to go.